Recent online discussions have frequently centered on the possibility of a The Last of Us sequel. Despite mixed reactions to the second game, many hoped Naughty Dog would address criticisms in a potential The Last of Us Part III or explore the universe through a spin-off. However, a recent statement from Neil Druckmann surprised even the most dedicated fans.

In a joint interview with screenwriter Craig Mazin, Druckmann discussed both the HBO adaptation and the games themselves. He revealed his struggles following the sequel's release during the COVID-19 pandemic, describing feelings of unease and heightened sensitivity exacerbated by online engagement. He confessed to reading reviews and online discussions, leading to self-doubt and questioning the game's quality.

When asked about a potential third installment, Druckmann acknowledged the anticipated question, but offered a disheartening response: fans shouldn't expect another The Last of Us game, implying the franchise may have reached its conclusion.